Description
Aromasin Breast Cancer Treatment
Aromasin (Exemestane) is a prescription medication used to treat certain types of breast cancer, primarily in postmenopausal women. It is classified as an aromatase inhibitor, which works by decreasing the production of estrogen in the body, a hormone that can promote the growth of hormone receptor-positive breast cancer.
Key Information About Aromasin:
Uses:
- Breast Cancer Treatment: Aromasin is commonly prescribed for postmenopausal women with estrogen receptor-positive (ER+) breast cancer. It is typically used after surgery or other treatments, such as chemotherapy, to reduce the risk of cancer recurrence.
- Early and Advanced Breast Cancer: Aromasin can be used for both early-stage breast cancer as well as advanced or metastatic breast cancer that has spread to other parts of the body.
- Prevention of Recurrence: For women who have already been treated with another hormonal therapy (e.g., Tamoxifen), Aromasin may be used to further reduce the chances of cancer returning.
Mechanism of Action:
- Aromasin works by inhibiting the enzyme aromatase, which is responsible for converting androgens into estrogen in the body. By blocking this conversion, Aromasin lowers estrogen levels, which can help slow or stop the growth of hormone-dependent breast cancer cells.
Dosage and Administration:
- Standard Dosage: Typically, Aromasin is taken once daily, often in a dose of 25 mg. It is usually taken after a meal to improve absorption.
- Duration: The duration of treatment can vary but is often prescribed for 2 to 5 years, depending on the individual case.
Common Side Effects:
- Hot flashes
- Joint and muscle pain
- Fatigue
- Bone thinning or osteoporosis (long-term use)
- Nausea
- Increased sweating
Less Common but Serious Side Effects:
- Bone fractures
- Depression or mood changes
- Liver issues
- Cardiovascular problems (for those at risk)
Comparisons:
- Aromasin is often compared to other aromatase inhibitors like Letrozole and Anastrozole. While all three medications work similarly by lowering estrogen levels, they may have slightly different side effect profiles and efficacy rates.
Who Should Not Take Aromasin:
- Pre-menopausal women (since Aromasin is specifically for postmenopausal women)
- People with known hypersensitivity to Exemestane or any other ingredient in the medication.
Monitoring:
- Patients on Aromasin often need regular monitoring, including bone density tests (due to the risk of osteoporosis) and liver function tests.
Purchasing Aromasin:
In the USA, Aromasin is available through prescription and can be bought at pharmacies, including online options. Insurance coverage may vary, and generic versions (Exemestane) are typically more affordable.
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